Dyshidrotic eczema common form of eczema causes small, intensely itchy blisters on the edges of the fingers, toes, palms, and soles of the feet. It is is twice as common in women as it is in men. Because of the association with seasonal allergies, the dyshidrotic eczema blisters are known to erupt more frequently during the spring allergy season. The blisters may last up to three weeks before they begin to dry and can sometimes be large and painful. As the blisters dry, they may turn into skin cracks or cause the skin to feel thick and spongy, especially if you’ve been scratching the area.